TEAD4 establishes the energy homeostasis essential for blastocoel formation
نویسندگان
چکیده
منابع مشابه
The earliest cell differentiation event in mammalian development occurs during preimplantation development when the outer blastomeres of the embryo form a monolayer of epithelial cells
INTRODUCTION The earliest cell differentiation event in mammalian development occurs during preimplantation development when the outer blastomeres of the embryo form a monolayer of epithelial cells [trophectoderm (TE)] that envelops the remaining blastomeres [inner cell mass (ICM)]. In mice, TE specification occurs in the 8to 16-cell compacted morula. Developmental transition to blastocyst stag...
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SH2B1 (previously named SH2-B), a cytoplasmic adaptor protein, binds via its Src homology 2 (SH2) domain to a variety of protein tyrosine kinases, including JAK2 and the insulin receptor. SH2B1-deficient mice are obese and diabetic. Here we demonstrated that multiple isoforms of SH2B1 (alpha, beta, gamma, and/or delta) were expressed in numerous tissues, including the brain, hypothalamus, liver...
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The development of the blastocoel in Xenopus laevis was studied by electron microscopy. Two major morphological specializations were associated both with blastocoel formation and with cleavage. The first specialization was the formation of close junctions at specific points along cleavage furrows, starting as early as the first division. The second was the secretion of material into the blastoc...
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ژورنال
عنوان ژورنال: Development
سال: 2013
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.093799